Organic Acids
Medchemexpress LLC DV1 TFA | 98.5% | 2424.85 | 5 MG
DV1 TFA is a selective antagonist for CXC chemokine receptor 4 (CXCR4) and exhibits antiviral activity. This product is for research use only and has not been fully validated for medical applications.
- Selective antagonist for CXC chemokine receptor 4 (CXCR4)
- Exhibits antiviral activity
- For research use only
Medchemexpress LLC Ecallantide TFA | 9007-83-4 | 99.54% | 7053.81 | 50 MG
Ecallantide TFA is a specific recombinant plasma kallikrein inhibitor that works by inhibiting the production of bradykinin, thereby offering a potential treatment for acute attacks of angioedema.
- Specific recombinant plasma kallikrein inhibitor
- Inhibits the production of bradykinin
- May be used to prevent acute attacks of angioedema
Medchemexpress LLC GRL-1720 TFA | 2835511-03-8 | C16H12ClF3N2O4 | 5 MG
GRL-1720 TFA is a potent inhibitor of SARS-CoV-2 Mpro, exhibiting anti-SARS-CoV2 activity with an EC50 value of 15 μM. This compound has a molecular weight of 388.73 and appears as a solid, ranging from light brown to brown in color.
- High purity of 98.94%.
- Shipped at room temperature.
- Store at -20°C, sealed, away from moisture.
- In solution, stable for 6 months at -80°C or 1 month at -20°C with sealed storage, away from moisture.
Medchemexpress LLC KRFK TFA | 99.8% | 577.73 (free base) | 5 MG
KRFK TFA is a peptide derived from TSP-1 that activates TGF-β. It promotes TGF-β-mediated signaling and its downstream role, independently of thrombospondin (TSP) receptors like CD47 and CD36. KRFK TFA is used in research for chronic ocular surface inflammatory disorders.
- Activates TGF-β.
- Promotes TGF-β-mediated signaling.
- Acts independently of thrombospondin (TSP) receptors (CD47 and CD36).
- Can be used for chronic ocular surface inflammatory disorders research.
Medchemexpress LLC PZ703b trifluoroacetate | 98.6% | 1714.46 g/mol | C82H103ClF6N10O13S4 | 5 MG
PZ703b TFA is a Bcl-xL-targeting PROTAC degrader provided for laboratory research use. It induces rapid BCL-XL degradation, triggers caspase-3-mediated apoptosis, and inhibits cancer cell proliferation in vitro, including activity in bladder cancer models and hematologic cell lines. Supplied as a trifluoroacetate salt, it is intended for biochemical and cell-based studies only.
- Bcl-xL PROTAC degrader that promotes targeted protein degradation.
- Induces caspase-3-mediated apoptosis in susceptible cell lines.
- Inhibits cell proliferation and can act synergistically with other small-molecule inhibitors in vitro.
- Demonstrated low-nanomolar cellular potency in selected hematologic cell lines.
- High purity (>98%) suitable for biochemical and cell-based assays.
- Available in small milligram pack sizes for research use only.
Medchemexpress LLC RVG TFA | 99.3% | 3266.62 | 5 MG
RVG TFA is a peptide derived from Rabies Virus Glycoprotein. It binds to the α-7 subunit of nicotinic acetylcholine receptors (AchR) of neuronal cells and enhances the delivery of *Mycobacterium tuberculosis* antigens to antigen-presenting cells.
- Binds to α-7 subunit of nicotinic acetylcholine receptors
- Enhances delivery of *Mycobacterium tuberculosis* antigens
- Appears as a solid
- Color: white to off-white
- Soluble in water at ≥ 100 mg/mL
- For research use only
Medchemexpress LLC KS-133 (TFA) | 98.95% | 1672.93 | 1 MG
KS-133 TFA is a highly selective and potent antagonist of the vascular active enteropeptide receptor 2 (VIPR2). It reverses the tumor-promoting M2 phenotype of tumor-associated macrophages to the anti-tumor M1 phenotype, alters the tumor immune microenvironment, and inhibits tumor growth. It is suitable for research on schizophrenia and cancer immune regulation.
- Highly selective and potent VIPR2 antagonist
- IC50 values for Ca influx measurement: 24.8 nM; cAMP measurement: 500 nM
- Reverses M2 to M1 macrophage phenotype
- Alters tumor immune microenvironment and inhibits tumor growth
- Inhibits excessive VIPR2 activation, preventing cognitive impairments and neuronal damage
- Demonstrates anti-tumor activity and synergistic effects with anti-PD-1 antibodies
Medchemexpress LLC Gmprga Tfa | 98.1% | 5 MG
GMPRGA TFA is the trifluoroacetic acid (TFA) salt form of GMPRGA. It is known to recognize spAimR in the bacterial cytosol, a process that induces lysogeny.
- TFA salt form
- Recognizes spAimR in bacterial cytosol
- Induces lysogeny
- Functions as an inhibitor
- Part of bacterial lysis-lysogeny studies
- Classified as an antimicrobial peptide
Medchemexpress LLC Thymotrinan trifluoroacetate | 00-00-0 | 98.7% | 531.48 g·mol⁻¹ | C18H32F3N7O8 | 25 MG
Thymotrinan TFA is a biologically active fragment of the thymus hormone thymopoietin, provided as the trifluoroacetate (TFA) salt for research use. It modulates immune responses, affecting both humoral and cellular immunity, and is supplied as a purified synthetic peptide for laboratory studies.
- Immunomodulating peptide that affects humoral and cellular responses.
- Supplied as the trifluoroacetate salt for improved stability and handling.
- High purity suitable for in vitro and preclinical research.
- Available in small-scale quantities for peptide research workflows.
- Molecular weight 531.48 g·mol⁻¹; formula C18H32F3N7O8.
Medchemexpress LLC Glycyl-exatecan (TFA) | 1883333-57-0 | 96.9% | 100 MG
Glycyl-Exatecan TFA is a derivative of Exatecan, known for its significant antitumor activity. This compound acts as an anticancer agent and is suitable for research applications, particularly in studies involving solid tumors.
- Acts as an anticancer agent
- Exhibits significant antitumor activity
- Suitable for solid tumors research
- Derivative of Exatecan
Medchemexpress LLC TP-5801 (TFA) | 99.6% | 641.48 | 25 MG
TP-5801 TFA is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor with an IC50 of 1.40 nM. This compound demonstrates anti-tumor activity and is suitable for various research applications.
- Inhibits TNK1-driven, BCR-ABL-driven, and IL-3-driven Ba/F3 cell growth.
- Inhibits TNK1-dependent L540 cell growth at low nM levels.
- Shows efficacy in mouse survival models, significantly prolonging lifespan.
- Inhibits localized tumor growth in mouse xenograft models.
Medchemexpress LLC Mazdutide TFA | 2259884-03-0 | 99.7% | 4563.06 | 1 MG
Mazdutide TFA is a long-acting synthetic oxyntomodulin analog. It acts as a co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR). It stimulates insulin secretion from mouse islets and is utilized in studies for obesity and type 2 diabetes (T2D).
- Acts as a co-agonist of GLP-1R and GCGR
- Stimulates insulin secretion from mouse islets
- Used in studies of obesity and type 2 diabetes
- Reduces body weight and physical intake in diabetic mice with diet-induced obesity
Medchemexpress LLC VU0364572 (TFA) | 1240514-89-9 | 99.3% | 487.51 | 25 MG
VU0364572 TFA is an orally active and selective allosteric agonist of the M1 muscarinic receptor with an EC50 of 0.11 μM. It demonstrates neuroprotective potential for preventing memory impairments and reducing neuropathology in Alzheimer's Disease and is CNS penetrant.
- Orally active and selective allosteric agonist of the M1 muscarinic receptor.
- Neuroprotective potential for preventing memory impairments.
- Reduces neuropathology in Alzheimer's Disease.
- CNS penetrant.
Medchemexpress LLC Ac-devd-cmk tfa | 98.6% | 664.97 | 5 MG
Ac-DEVD-CMK TFA is a selective and irreversible caspase-3 inhibitor. It significantly inhibits apoptosis induced by high levels of glucose or 3,20-dibenzoate, and can be used in various experimental approaches to inhibit apoptosis.
- Selective and irreversible caspase-3 inhibitor.
- Significantly inhibits apoptosis induced by high levels of glucose or 3,20-dibenzoate.
- Suitable for various experimental approaches to inhibit apoptosis.
- Inhibits IDB-induced apoptosis.
- Attenuates acetaminophen-induced liver injury.
- Mitigates liver damage by inhibiting GSK‐3β or caspase‐3 activity.
- Effective in inhibiting citrate-induced p21 cleavage and G2/M accumulation in human pharyngeal squamous carcinoma cell lines.
Medchemexpress LLC Spexin (Neuropeptide Q) | 1370290-58-6 | 99.9% | 1619.88 | 1 MG
Spexin (Neuropeptide Q) | 1370290-58-6 | 99.9% | 1619.88 | 1 MG